$500,000 worth of funding will be used to set up irrigation pipeline screens set to benefit irrigators, environmental groups and recreational fishers as well as endangered fish in the region's waterways.
The project, which has taken decades to progress to this stage, will erect fish screens over irrigation pipelines that exist along the Murray Darling waterway and is currently constructing fish screens for irrigators in the Trangie and Nevertire areas to benefit from.
Senior Fisheries Manager Sam Davis says the project could potentially save millions of fish from being extracted and in many cases destroyed from the region's water.
"Fish screens prevent fish from being entrained into our pump irrigation and our water channels," Ms Davis said.
"Those fish who are extracted are completely lost to the local ecosystem, they will never get to return, we lose all their genetic input and we can't get it back."
"Our scientists have worked at quantifying how many fish are lost, and at our best estimate, millions of fish are lost in these water systems every year."